2-oxoglutarate dehydrogenase-like, mitochondrial (OGDHL)
Homo sapiens — UniProt Q9ULD0
Data last refreshed: (UniProt release unknown)
Key facts
2-oxoglutarate dehydrogenase-like, mitochondrial (OGDHL) is a protein from Homo sapiens identified by UniProt accession Q9ULD0, 1010 residues long. MolForge cross-references it against 0 known binders and 76 disease associations.
- UniProt accession: Q9ULD0; gene symbol OGDHL.
- Organism: Homo sapiens.
- Length: 1010 amino acids.
- Top disease associations (Open Targets): Yoon-Bellen neurodevelopmental syndrome, cystatin C measurement and creatinine measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | 2-oxoglutarate dehydrogenase-like, mitochondrial |
|---|---|
| UniProt accession | Q9ULD0 |
| Gene | OGDHL |
| Organism | Homo sapiens |
| Length | 1010 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (76)
Diseases linked to this target (Open Targets).
- Yoon-Bellen neurodevelopmental syndrome · score 0.75
- cystatin C measurement · score 0.31
- creatinine measurement · score 0.28
- Abnormal brain morphology · score 0.27
- hematocrit · score 0.26
- genetic disorder · score 0.19
- unipolar depression · score 0.18
- depressive symptom measurement · score 0.18
- depressive disorder · score 0.18
- wellbeing measurement · score 0.17
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9ULD0-F1 | alphafold | PREDICTED | 90.04 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9ULD0.
Amino-acid sequence (1010 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with OGDHL?
The strongest Open Targets associations for OGDHL are Yoon-Bellen neurodevelopmental syndrome, cystatin C measurement, creatinine measurement, Abnormal brain morphology and hematocrit.
How long is the OGDHL protein?
The Homo sapiens OGDHL protein (UniProt Q9ULD0) is 1010 amino acids long.
Browse: Targets: O · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9ULD0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9ULD0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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