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Zinc finger protein 777 (ZNF777)

Homo sapiens — UniProt Q9ULD5

Gene: ZNF777Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Zinc finger protein 777 (ZNF777) is a protein from Homo sapiens identified by UniProt accession Q9ULD5, 831 residues long. MolForge cross-references it against 0 known binders and 17 disease associations.

  • UniProt accession: Q9ULD5; gene symbol ZNF777.
  • Organism: Homo sapiens.
  • Length: 831 amino acids.
  • Top disease associations (Open Targets): neurodegenerative disease, mean corpuscular volume and diastolic blood pressure.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameZinc finger protein 777
UniProt accessionQ9ULD5
GeneZNF777
OrganismHomo sapiens
Length831 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (17)

Diseases linked to this target (Open Targets).

  • neurodegenerative disease · score 0.45
  • mean corpuscular volume · score 0.42
  • diastolic blood pressure · score 0.40
  • mean corpuscular hemoglobin · score 0.38
  • mean corpuscular hemoglobin concentration · score 0.33
  • monocyte count · score 0.28
  • reticulocyte count · score 0.17
  • lymphocyte count · score 0.12
  • Immature Reticulocyte Fraction Measurement · score 0.11
  • reticulocyte measurement · score 0.11

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q9ULD5-F1alphafoldPREDICTED57.69—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9ULD5.

Amino-acid sequence (831 residues)

MENQRSSPLS FPSVPQEETL RQAPAGLPRE TLFQSRVLPP KEIPSLSPTI PRQGSLPQTS SAPKQETSGR MPHVLQKGPS LLCSAASEQE TSLQGPLASQ EGTQYPPPAA AEQEVSLLSH SPHHQEAPVH SPEAPEKDPL TLSPTVPETD MDPLLQSPVS QKDTPFQISS AVQKEQPLPT AEITRLAVWA AVQAVERKLE AQAMRLLTLE GRTGTNEKKI ADCEKTAVEF ANHLESKWVV LGTLLQEYGL LQRRLENMEN LLKNRNFWIL RLPPGSNGEV PKVPVTFDDV AVHFSEQEWG NLSEWQKELY KNVMRGNYES LVSMDYAISK PDLMSQMERG ERPTMQEQED SEEGETPTDP SAAHDGIVIK IEVQTNDEGS ESLETPEPLM GQVEEHGFQD SELGDPCGEQ PDLDMQEPEN TLEESTEGSS EFSELKQMLV QQRNCTEGIV IKTEEQDEEE EEEEEDELPQ HLQSLGQLSG RYEASMYQTP LPGEMSPEGE ESPPPLQLGN PAVKRLAPSV HGERHLSENR GASSQQQRNR RGERPFTCME CGKSFRLKIN LIIHQRNHIK EGPYECAECE ISFRHKQQLT LHQRIHRVRG GCVSPERGPT FNPKHALKPR PKSPSSGSGG GGPKPYKCPE CDSSFSHKSS LTKHQITHTG ERPYTCPECK KSFRLHISLV IHQRVHAGKH EVSFICSLCG KSFSRPSHLL RHQRTHTGER PFKCPECEKS FSEKSKLTNH CRVHSRERPH ACPECGKSFI RKHHLLEHRR IHTGERPYHC AECGKRFTQK HHLLEHQRAH TGERPYPCTH CAKCFRYKQS LKYHLRTHTG E

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with ZNF777?

The strongest Open Targets associations for ZNF777 are neurodegenerative disease, mean corpuscular volume, diastolic blood pressure, mean corpuscular hemoglobin and mean corpuscular hemoglobin concentration.

How long is the ZNF777 protein?

The Homo sapiens ZNF777 protein (UniProt Q9ULD5) is 831 amino acids long.

Browse: Targets: Z · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ9ULD5
GeneZNF777
OrganismHomo sapiens
Length831
Binders0
Diseases17
View on UniProt