Protein inturned (INTU)
Homo sapiens — UniProt Q9ULD6
Data last refreshed: (UniProt release unknown)
Key facts
Protein inturned (INTU) is a protein from Homo sapiens identified by UniProt accession Q9ULD6, 942 residues long. MolForge cross-references it against 0 known binders and 151 disease associations.
- UniProt accession: Q9ULD6; gene symbol INTU.
- Organism: Homo sapiens.
- Length: 942 amino acids.
- Top disease associations (Open Targets): short rib dysplasia, orofaciodigital syndrome and vital capacity.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Protein inturned |
|---|---|
| UniProt accession | Q9ULD6 |
| Gene | INTU |
| Organism | Homo sapiens |
| Length | 942 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (151)
Diseases linked to this target (Open Targets).
- short rib dysplasia · score 0.47
- orofaciodigital syndrome · score 0.46
- vital capacity · score 0.40
- mean corpuscular volume · score 0.39
- Short rib-polydactyly syndrome, Verma-Naumoff type · score 0.37
- short-rib thoracic dysplasia 7/20 with polydactyly, digenic · score 0.33
- neurodegenerative disease · score 0.33
- short rib-polydactyly syndrome · score 0.32
- mean corpuscular hemoglobin · score 0.32
- Growth delay · score 0.26
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9ULD6-F1 | alphafold | PREDICTED | 66.93 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9ULD6.
Amino-acid sequence (942 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with INTU?
The strongest Open Targets associations for INTU are short rib dysplasia, orofaciodigital syndrome, vital capacity, mean corpuscular volume and Short rib-polydactyly syndrome, Verma-Naumoff type.
How long is the INTU protein?
The Homo sapiens INTU protein (UniProt Q9ULD6) is 942 amino acids long.
Browse: Targets: I · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9ULD6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9ULD6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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