Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 (ASAP1)
Homo sapiens — UniProt Q9ULH1
Data last refreshed: (UniProt release unknown)
Key facts
Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 (ASAP1) is a protein from Homo sapiens identified by UniProt accession Q9ULH1, 1129 residues long. MolForge cross-references it against 0 known binders and 228 disease associations.
- UniProt accession: Q9ULH1; gene symbol ASAP1.
- Organism: Homo sapiens.
- Length: 1129 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, mean platelet volume and refractive error measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 |
|---|---|
| UniProt accession | Q9ULH1 |
| Gene | ASAP1 |
| Organism | Homo sapiens |
| Length | 1129 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (228)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.50
- mean platelet volume · score 0.45
- refractive error measurement · score 0.44
- FEV/FVC ratio · score 0.42
- platelet component distribution width · score 0.38
- tuberculosis · score 0.38
- body height · score 0.34
- mean corpuscular volume · score 0.32
- Red cell distribution width · score 0.31
- leukocyte count · score 0.30
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9ULH1-F1 | alphafold | PREDICTED | 71.33 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9ULH1.
Amino-acid sequence (1129 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ASAP1?
The strongest Open Targets associations for ASAP1 are neurodegenerative disease, mean platelet volume, refractive error measurement, FEV/FVC ratio and platelet component distribution width.
How long is the ASAP1 protein?
The Homo sapiens ASAP1 protein (UniProt Q9ULH1) is 1129 amino acids long.
Browse: Targets: A · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9ULH1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9ULH1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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