Myocardin-related transcription factor B (MRTFB)
Homo sapiens — UniProt Q9ULH7
Data last refreshed: (UniProt release unknown)
Key facts
Myocardin-related transcription factor B (MRTFB) is a protein from Homo sapiens identified by UniProt accession Q9ULH7, 1088 residues long. MolForge cross-references it against 0 known binders and 203 disease associations.
- UniProt accession: Q9ULH7; gene symbol MRTFB.
- Organism: Homo sapiens.
- Length: 1088 amino acids.
- Top disease associations (Open Targets): body height, puberty onset measurement and age at menarche.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Myocardin-related transcription factor B |
|---|---|
| UniProt accession | Q9ULH7 |
| Gene | MRTFB |
| Organism | Homo sapiens |
| Length | 1088 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (203)
Diseases linked to this target (Open Targets).
- body height · score 0.33
- puberty onset measurement · score 0.32
- age at menarche · score 0.31
- balding measurement · score 0.29
- PHF-tau measurement · score 0.28
- appendicular lean mass · score 0.28
- age at voice drop · score 0.27
- androgenetic alopecia · score 0.27
- hair shape measurement · score 0.25
- BMI-adjusted waist circumference · score 0.24
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9ULH7-F1 | alphafold | PREDICTED | 52.25 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9ULH7.
Amino-acid sequence (1088 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with MRTFB?
The strongest Open Targets associations for MRTFB are body height, puberty onset measurement, age at menarche, balding measurement and PHF-tau measurement.
How long is the MRTFB protein?
The Homo sapiens MRTFB protein (UniProt Q9ULH7) is 1088 amino acids long.
Browse: Targets: M · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9ULH7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9ULH7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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