ATPase family AAA domain-containing protein 2B (ATAD2B)
Homo sapiens — UniProt Q9ULI0
Data last refreshed: (UniProt release unknown)
Key facts
ATPase family AAA domain-containing protein 2B (ATAD2B) is a protein from Homo sapiens identified by UniProt accession Q9ULI0, 1458 residues long. MolForge cross-references it against 0 known binders and 87 disease associations.
- UniProt accession: Q9ULI0; gene symbol ATAD2B.
- Organism: Homo sapiens.
- Length: 1458 amino acids.
- Top disease associations (Open Targets): mean corpuscular volume, body height and reticulocyte count.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | ATPase family AAA domain-containing protein 2B |
|---|---|
| UniProt accession | Q9ULI0 |
| Gene | ATAD2B |
| Organism | Homo sapiens |
| Length | 1458 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (87)
Diseases linked to this target (Open Targets).
- mean corpuscular volume · score 0.36
- body height · score 0.36
- reticulocyte count · score 0.36
- lean body mass · score 0.33
- HbA1c measurement · score 0.32
- mean reticulocyte volume · score 0.32
- mean platelet volume · score 0.31
- lymphocyte count · score 0.31
- mean corpuscular hemoglobin · score 0.30
- birth weight · score 0.26
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9ULI0-F1 | alphafold | PREDICTED | 59.98 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9ULI0.
Amino-acid sequence (1458 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ATAD2B?
The strongest Open Targets associations for ATAD2B are mean corpuscular volume, body height, reticulocyte count, lean body mass and HbA1c measurement.
How long is the ATAD2B protein?
The Homo sapiens ATAD2B protein (UniProt Q9ULI0) is 1458 amino acids long.
Browse: Targets: A · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9ULI0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9ULI0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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