Protein HEG homolog 1 (HEG1)
Homo sapiens — UniProt Q9ULI3
Data last refreshed: (UniProt release unknown)
Key facts
Protein HEG homolog 1 (HEG1) is a protein from Homo sapiens identified by UniProt accession Q9ULI3, 1381 residues long. MolForge cross-references it against 0 known binders and 141 disease associations.
- UniProt accession: Q9ULI3; gene symbol HEG1.
- Organism: Homo sapiens.
- Length: 1381 amino acids.
- Top disease associations (Open Targets): gut microbiome measurement, erythrocyte count and cystatin C measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Protein HEG homolog 1 |
|---|---|
| UniProt accession | Q9ULI3 |
| Gene | HEG1 |
| Organism | Homo sapiens |
| Length | 1381 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (141)
Diseases linked to this target (Open Targets).
- gut microbiome measurement · score 0.34
- erythrocyte count · score 0.32
- cystatin C measurement · score 0.31
- creatinine measurement · score 0.29
- Immature Reticulocyte Fraction Measurement · score 0.28
- red blood cell density measurement · score 0.28
- hemoglobin measurement · score 0.28
- visceral adipose tissue measurement · score 0.23
- hematocrit · score 0.23
- reticulocyte count · score 0.12
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9ULI3-F1 | alphafold | PREDICTED | 42.24 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9ULI3.
Amino-acid sequence (1381 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with HEG1?
The strongest Open Targets associations for HEG1 are gut microbiome measurement, erythrocyte count, cystatin C measurement, creatinine measurement and Immature Reticulocyte Fraction Measurement.
How long is the HEG1 protein?
The Homo sapiens HEG1 protein (UniProt Q9ULI3) is 1381 amino acids long.
Browse: Targets: H · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9ULI3 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9ULI3 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.