Zinc finger and BTB domain-containing protein 21 (ZBTB21)
Homo sapiens — UniProt Q9ULJ3
Data last refreshed: (UniProt release unknown)
Key facts
Zinc finger and BTB domain-containing protein 21 (ZBTB21) is a protein from Homo sapiens identified by UniProt accession Q9ULJ3, 1066 residues long. MolForge cross-references it against 0 known binders and 33 disease associations.
- UniProt accession: Q9ULJ3; gene symbol ZBTB21.
- Organism: Homo sapiens.
- Length: 1066 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, red blood cell density measurement and monocyte count.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Zinc finger and BTB domain-containing protein 21 |
|---|---|
| UniProt accession | Q9ULJ3 |
| Gene | ZBTB21 |
| Organism | Homo sapiens |
| Length | 1066 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (33)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.37
- red blood cell density measurement · score 0.22
- monocyte count · score 0.20
- mean reticulocyte volume · score 0.18
- Dravet syndrome · score 0.05
- lymphocyte count · score 0.04
- systolic blood pressure · score 0.02
- Cognitive impairment · score 0.02
- Down syndrome · score 0.01
- psoriasis · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9ULJ3-F1 | alphafold | PREDICTED | 53.19 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9ULJ3.
Amino-acid sequence (1066 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ZBTB21?
The strongest Open Targets associations for ZBTB21 are neurodegenerative disease, red blood cell density measurement, monocyte count, mean reticulocyte volume and Dravet syndrome.
How long is the ZBTB21 protein?
The Homo sapiens ZBTB21 protein (UniProt Q9ULJ3) is 1066 amino acids long.
Browse: Targets: Z · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9ULJ3 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9ULJ3 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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