Zinc finger MIZ domain-containing protein 1 (ZMIZ1)
Homo sapiens — UniProt Q9ULJ6
Data last refreshed: (UniProt release unknown)
Key facts
Zinc finger MIZ domain-containing protein 1 (ZMIZ1) is a protein from Homo sapiens identified by UniProt accession Q9ULJ6, 1067 residues long. MolForge cross-references it against 0 known binders and 179 disease associations.
- UniProt accession: Q9ULJ6; gene symbol ZMIZ1.
- Organism: Homo sapiens.
- Length: 1067 amino acids.
- Top disease associations (Open Targets): neurodevelopmental disorder with dysmorphic facies and distal skeletal anomalies, genetic disorder and electrocardiography.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Zinc finger MIZ domain-containing protein 1 |
|---|---|
| UniProt accession | Q9ULJ6 |
| Gene | ZMIZ1 |
| Organism | Homo sapiens |
| Length | 1067 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (179)
Diseases linked to this target (Open Targets).
- neurodevelopmental disorder with dysmorphic facies and distal skeletal anomalies · score 0.74
- genetic disorder · score 0.49
- electrocardiography · score 0.47
- BMI-adjusted waist-hip ratio · score 0.46
- complex neurodevelopmental disorder · score 0.46
- Intellectual disability · score 0.46
- type 2 diabetes mellitus · score 0.46
- body height · score 0.46
- BMI-adjusted waist circumference · score 0.45
- breast carcinoma · score 0.45
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9ULJ6-F1 | alphafold | PREDICTED | 57.28 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9ULJ6.
Amino-acid sequence (1067 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ZMIZ1?
The strongest Open Targets associations for ZMIZ1 are neurodevelopmental disorder with dysmorphic facies and distal skeletal anomalies, genetic disorder, electrocardiography, BMI-adjusted waist-hip ratio and complex neurodevelopmental disorder.
How long is the ZMIZ1 protein?
The Homo sapiens ZMIZ1 protein (UniProt Q9ULJ6) is 1067 amino acids long.
Browse: Targets: Z · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9ULJ6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9ULJ6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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