Ankyrin repeat domain-containing protein 50 (ANKRD50)
Homo sapiens — UniProt Q9ULJ7
Data last refreshed: (UniProt release unknown)
Key facts
Ankyrin repeat domain-containing protein 50 (ANKRD50) is a protein from Homo sapiens identified by UniProt accession Q9ULJ7, 1429 residues long. MolForge cross-references it against 0 known binders and 42 disease associations.
- UniProt accession: Q9ULJ7; gene symbol ANKRD50.
- Organism: Homo sapiens.
- Length: 1429 amino acids.
- Top disease associations (Open Targets): heel bone mineral density, gastric carcinoma and neurofibrillary tangles measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Ankyrin repeat domain-containing protein 50 |
|---|---|
| UniProt accession | Q9ULJ7 |
| Gene | ANKRD50 |
| Organism | Homo sapiens |
| Length | 1429 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (42)
Diseases linked to this target (Open Targets).
- heel bone mineral density · score 0.36
- gastric carcinoma · score 0.33
- neurofibrillary tangles measurement · score 0.30
- type 1 diabetes mellitus · score 0.26
- brain measurement · score 0.25
- BMI-adjusted waist-hip ratio · score 0.21
- waist-hip ratio · score 0.19
- vital capacity · score 0.19
- hair shape measurement · score 0.16
- forced expiratory volume · score 0.16
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9ULJ7-F1 | alphafold | PREDICTED | 73.94 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9ULJ7.
Amino-acid sequence (1429 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ANKRD50?
The strongest Open Targets associations for ANKRD50 are heel bone mineral density, gastric carcinoma, neurofibrillary tangles measurement, type 1 diabetes mellitus and brain measurement.
How long is the ANKRD50 protein?
The Homo sapiens ANKRD50 protein (UniProt Q9ULJ7) is 1429 amino acids long.
Browse: Targets: A · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9ULJ7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9ULJ7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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