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Glutamate receptor ionotropic, delta-1 (GRID1)

Homo sapiens — UniProt Q9ULK0

Gene: GRID1Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Glutamate receptor ionotropic, delta-1 (GRID1) is a protein from Homo sapiens identified by UniProt accession Q9ULK0, 1009 residues long. MolForge cross-references it against 0 known binders and 86 disease associations.

  • UniProt accession: Q9ULK0; gene symbol GRID1.
  • Organism: Homo sapiens.
  • Length: 1009 amino acids.
  • Top disease associations (Open Targets): body mass index, body height and vitamin D measurement.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameGlutamate receptor ionotropic, delta-1
UniProt accessionQ9ULK0
GeneGRID1
OrganismHomo sapiens
Length1009 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (86)

Diseases linked to this target (Open Targets).

  • body mass index · score 0.49
  • body height · score 0.47
  • vitamin D measurement · score 0.47
  • adolescent idiopathic scoliosis · score 0.44
  • body weight · score 0.43
  • fat body mass · score 0.41
  • type 2 diabetes mellitus · score 0.39
  • lean body mass · score 0.37
  • body fat percentage · score 0.36
  • PHF-tau measurement · score 0.34

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q9ULK0-F1alphafoldPREDICTED75.04—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9ULK0.

Amino-acid sequence (1009 residues)

MEALTLWLLP WICQCVSVRA DSIIHIGAIF EENAAKDDRV FQLAVSDLSL NDDILQSEKI TYSIKVIEAN NPFQAVQEAC DLMTQGILAL VTSTGCASAN ALQSLTDAMH IPHLFVQRNP GGSPRTACHL NPSPDGEAYT LASRPPVRLN DVMLRLVTEL RWQKFVMFYD SEYDIRGLQS FLDQASRLGL DVSLQKVDKN ISHVFTSLFT TMKTEELNRY RDTLRRAILL LSPQGAHSFI NEAVETNLAS KDSHWVFVNE EISDPEILDL VHSALGRMTV VRQIFPSAKD NQKCTRNNHR ISSLLCDPQE GYLQMLQISN LYLYDSVLML ANAFHRKLED RKWHSMASLN CIRKSTKPWN GGRSMLDTIK KGHITGLTGV MEFREDSSNP YVQFEILGTT YSETFGKDMR KLATWDSEKG LNGSLQERPM GSRLQGLTLK VVTVLEEPFV MVAENILGQP KRYKGFSIDV LDALAKALGF KYEIYQAPDG RYGHQLHNTS WNGMIGELIS KRADLAISAI TITPERESVV DFSKRYMDYS VGILIKKPEE KISIFSLFAP FDFAVWACIA AAIPVVGVLI FVLNRIQAVR AQSAAQPRPS ASATLHSAIW IVYGAFVQQG GESSVNSMAM RIVMGSWWLF TLIVCSSYTA NLAAFLTVSR MDNPIRTFQD LSKQVEMSYG TVRDSAVYEY FRAKGTNPLE QDSTFAELWR TISKNGGADN CVSSPSEGIR KAKKGNYAFL WDVAVVEYAA LTDDDCSVTV IGNSISSKGY GIALQHGSPY RDLFSQRILE LQDTGDLDVL KQKWWPHMGR CDLTSHASAQ ADGKSLKLHS FAGVFCILAI GLLLACLVAA LELWWNSNRC HQETPKEDKE VNLEQVHRRM NSLMDEDIAH KQISPASIEL SALEMGGLAP TQTLEPTREY QNTQLSVSTF LPEQSSHGTS RTLSSGPSSN LPLPLSSSAT MPSMQCKHRS PNGGLFRQSP VKTPIPMSFQ PVPGGVLPEA LDTSHGTSI

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with GRID1?

The strongest Open Targets associations for GRID1 are body mass index, body height, vitamin D measurement, adolescent idiopathic scoliosis and body weight.

How long is the GRID1 protein?

The Homo sapiens GRID1 protein (UniProt Q9ULK0) is 1009 amino acids long.

Browse: Targets: G · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ9ULK0
GeneGRID1
OrganismHomo sapiens
Length1009
Binders0
Diseases86
View on UniProt