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RING finger protein 150 (RNF150)

Homo sapiens — UniProt Q9ULK6

Gene: RNF150Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

RING finger protein 150 (RNF150) is a protein from Homo sapiens identified by UniProt accession Q9ULK6, 438 residues long. MolForge cross-references it against 0 known binders and 32 disease associations.

  • UniProt accession: Q9ULK6; gene symbol RNF150.
  • Organism: Homo sapiens.
  • Length: 438 amino acids.
  • Top disease associations (Open Targets): platelet count, trauma complication and injury.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameRING finger protein 150
UniProt accessionQ9ULK6
GeneRNF150
OrganismHomo sapiens
Length438 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (32)

Diseases linked to this target (Open Targets).

  • platelet count · score 0.37
  • trauma complication · score 0.33
  • injury · score 0.33
  • platelet crit · score 0.31
  • Abnormality of refraction · score 0.29
  • BMI-adjusted hip circumference · score 0.23
  • PHF-tau measurement · score 0.06
  • protein measurement · score 0.05
  • colorectal cancer · score 0.03
  • chronic obstructive pulmonary disease · score 0.03

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q9ULK6-F1alphafoldPREDICTED75.15—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9ULK6.

Amino-acid sequence (438 residues)

MAMSLIQACC SLALSTWLLS FCFVHLLCLD FTVAEKEEWY TAFVNITYAE PAPDPGAGAA GGGGAELHTE KTECGRYGEH SPKQDARGEV VMASSAHDRL ACDPNTKFAA PTRGKNWIAL IPKGNCTYRD KIRNAFLQNA SAVVIFNVGS NTNETITMPH AGVEDIVAIM IPEPKGKEIV SLLERNITVT MYITIGTRNL QKYVSRTSVV FVSISFIVLM IISLAWLVFY YIQRFRYANA RDRNQRRLGD AAKKAISKLQ IRTIKKGDKE TESDFDNCAV CIEGYKPNDV VRILPCRHLF HKSCVDPWLL DHRTCPMCKM NILKALGIPP NADCMDDLPT DFEGSLGGPP TNQITGASDT TVNESSVTLD PAVRTVGALQ VVQDTDPIPQ EGDVIFTTNS EQEPAVSSDS DISLIMAMEV GLSDVELSTD QDCEEVKS

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with RNF150?

The strongest Open Targets associations for RNF150 are platelet count, trauma complication, injury, platelet crit and Abnormality of refraction.

How long is the RNF150 protein?

The Homo sapiens RNF150 protein (UniProt Q9ULK6) is 438 amino acids long.

Browse: Targets: R · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ9ULK6
GeneRNF150
OrganismHomo sapiens
Length438
Binders0
Diseases32
View on UniProt