Zinc finger protein 490 (ZNF490)
Homo sapiens — UniProt Q9ULM2
Data last refreshed: (UniProt release unknown)
Key facts
Zinc finger protein 490 (ZNF490) is a protein from Homo sapiens identified by UniProt accession Q9ULM2, 529 residues long. MolForge cross-references it against 0 known binders and 40 disease associations.
- UniProt accession: Q9ULM2; gene symbol ZNF490.
- Organism: Homo sapiens.
- Length: 529 amino acids.
- Top disease associations (Open Targets): emphysema, body height and mean corpuscular hemoglobin.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Zinc finger protein 490 |
|---|---|
| UniProt accession | Q9ULM2 |
| Gene | ZNF490 |
| Organism | Homo sapiens |
| Length | 529 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (40)
Diseases linked to this target (Open Targets).
- emphysema · score 0.19
- body height · score 0.19
- mean corpuscular hemoglobin · score 0.17
- genetic disorder · score 0.12
- Abnormal central motor function · score 0.10
- retinitis pigmentosa · score 0.07
- Leber congenital amaurosis · score 0.05
- aniridia · score 0.05
- Aniridia-intellectual disability syndrome · score 0.04
- Familial ocular anterior segment mesenchymal dysgenesis · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9ULM2-F1 | alphafold | PREDICTED | 71.43 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9ULM2.
Amino-acid sequence (529 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ZNF490?
The strongest Open Targets associations for ZNF490 are emphysema, body height, mean corpuscular hemoglobin, genetic disorder and Abnormal central motor function.
How long is the ZNF490 protein?
The Homo sapiens ZNF490 protein (UniProt Q9ULM2) is 529 amino acids long.
Browse: Targets: Z · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9ULM2 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9ULM2 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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