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YEATS domain-containing protein 2 (YEATS2)

Homo sapiens — UniProt Q9ULM3

Gene: YEATS2Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

YEATS domain-containing protein 2 (YEATS2) is a protein from Homo sapiens identified by UniProt accession Q9ULM3, 1422 residues long. MolForge cross-references it against 0 known binders and 74 disease associations.

  • UniProt accession: Q9ULM3; gene symbol YEATS2.
  • Organism: Homo sapiens.
  • Length: 1422 amino acids.
  • Top disease associations (Open Targets): benign adult familial myoclonic epilepsy, breast adenocarcinoma and systolic blood pressure.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameYEATS domain-containing protein 2
UniProt accessionQ9ULM3
GeneYEATS2
OrganismHomo sapiens
Length1422 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (74)

Diseases linked to this target (Open Targets).

  • benign adult familial myoclonic epilepsy · score 0.41
  • breast adenocarcinoma · score 0.22
  • systolic blood pressure · score 0.22
  • body mass index · score 0.17
  • mean arterial pressure · score 0.16
  • body height · score 0.14
  • body fat percentage · score 0.13
  • acute myeloid leukemia · score 0.12
  • breast ductal adenocarcinoma · score 0.11
  • sex hormone-binding globulin measurement · score 0.11

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q9ULM3-F1alphafoldPREDICTED49.84—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9ULM3.

Amino-acid sequence (1422 residues)

MSGIKRTIKE TDPDYEDVSV ALPNKRHKAI ENSARDAAVQ KIETIIKEQF ALEMKNKEHE IEVIDQRLIE ARRMMDKLRA CIVANYYASA GLLKVSEGSK TCDTMVFNHP AIKKFLESPS RSSSPANQRA ETPSANHSES DSLSQHNDFL SDKDNNSNMD IEERLSNNME QRPSRNTGRD TSRITGSHKT EQRNADLTDE TSRLFVKKTI VVGNVSKYIP PDKREENDQS THKWMVYVRG SRREPSINHF VKKVWFFLHP SYKPNDLVEV REPPFHLTRR GWGEFPVRVQ VHFKDSQNKR IDIIHNLKLD RTYTGLQTLG AETVVDVELH RHSLGEDCIY PQSSESDISD APPSLPLTIP APVKASSPIK QSHEPVPDTS VEKGFPASTE AERHTPFYAL PSSLERTPTK MTTSQKVTFC SHGNSAFQPI ASSCKIVPQS QVPNPESPGK SFQPITMSCK IVSGSPISTP SPSPLPRTPT STPVHVKQGT AGSVINNPYV IMDKQPGQVI GATTPSTGSP TNKISTASQV SQGTGSPVPK IHGSSFVTST VKQEDSLFAS MPPLCPIGSH PKVQSPKPIT GGLGAFTKVI IKQEPGEAPH VPATGAASQS PLPQYVTVKG GHMIAVSPQK QVITPGEGIA QSAKVQPSKV VGVPVGSALP STVKQAVAIS GGQILVAKAS SSVSKAVGPK QVVTQGVAKA IVSGGGGTIV AQPVQTLTKA QVTAAGPQKS GSQGSVMATL QLPATNLANL ANLPPGTKLY LTTNSKNPSG KGKLLLIPQG AILRATNNAN LQSGSAASGG SGAGGGGGGG GGGGSGSGGG GSTGGGGGTA GGGTQSTAGP GGISQHLTYT SYILKQTPQG TFLVGQPSPQ TSGKQLTTGS VVQGTLGVST SSAQGQQTLK VISGQKTTLF TQAAHGGQAS LMKISDSTLK TVPATSQLSK PGTTMLRVAG GVITTATSPA VALSANGPAQ QSEGMAPVSS STVSSVTKTS GQQQVCVSQA TVGTCKAATP TVVSATSLVP TPNPISGKAT VSGLLKIHSS QSSPQQAVLT IPSQLKPLSV NTSGGVQTIL MPVNKVVQSF STSKPPAILP VAAPTPVVPS SAPAAVAKVK TEPETPGPSC LSQEGQTAVK TEESSELGNY VIKIDHLETI QQLLTAVVKK IPLITAKSED ASCFSAKSVE QYYGWNIGKR RAAEWQRAMT MRKVLQEILE KNPRFHHLTP LKTKHIAHWC RCHGYTPPDP ESLRNDGDSI EDVLTQIDSE PECPSSFSSA DNLCRKLEDL QQFQKREPEN EEEVDILSLS EPVKINIKKE QEEKQEEVKF YLPPTPGSEF IGDVTQKIGI TLQPVALHRN VYASVVEDMI LKATEQLVND ILRQALAVGY QTASHNRIPK EITVSNIHQA ICNIPFLDFL TNKHMGILNE DQ

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with YEATS2?

The strongest Open Targets associations for YEATS2 are benign adult familial myoclonic epilepsy, breast adenocarcinoma, systolic blood pressure, body mass index and mean arterial pressure.

How long is the YEATS2 protein?

The Homo sapiens YEATS2 protein (UniProt Q9ULM3) is 1422 amino acids long.

Browse: Targets: Y · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ9ULM3
GeneYEATS2
OrganismHomo sapiens
Length1422
Binders0
Diseases74
View on UniProt