Paraneoplastic antigen-like protein 8B (PNMA8B)
Homo sapiens — UniProt Q9ULN7
Data last refreshed: (UniProt release unknown)
Key facts
Paraneoplastic antigen-like protein 8B (PNMA8B) is a protein from Homo sapiens identified by UniProt accession Q9ULN7, 635 residues long. MolForge cross-references it against 0 known binders and 21 disease associations.
- UniProt accession: Q9ULN7; gene symbol PNMA8B.
- Organism: Homo sapiens.
- Length: 635 amino acids.
- Top disease associations (Open Targets): chronotype measurement, C-reactive protein measurement and Immature Reticulocyte Fraction Measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Paraneoplastic antigen-like protein 8B |
|---|---|
| UniProt accession | Q9ULN7 |
| Gene | PNMA8B |
| Organism | Homo sapiens |
| Length | 635 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (21)
Diseases linked to this target (Open Targets).
- chronotype measurement · score 0.24
- C-reactive protein measurement · score 0.11
- Immature Reticulocyte Fraction Measurement · score 0.06
- P wave terminal force measurement · score 0.06
- reticulocyte count · score 0.04
- glioblastoma multiforme · score 0.03
- metabolite measurement · score 0.03
- body height · score 0.03
- reticulocyte measurement · score 0.03
- vital capacity · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9ULN7-F1 | alphafold | PREDICTED | 49.67 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9ULN7.
Amino-acid sequence (635 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with PNMA8B?
The strongest Open Targets associations for PNMA8B are chronotype measurement, C-reactive protein measurement, Immature Reticulocyte Fraction Measurement, P wave terminal force measurement and reticulocyte count.
How long is the PNMA8B protein?
The Homo sapiens PNMA8B protein (UniProt Q9ULN7) is 635 amino acids long.
Browse: Targets: P · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9ULN7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9ULN7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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