Polyadenylate-binding protein-interacting protein…

About Polyadenylate-binding protein-interacting protein 2B

Polyadenylate-binding protein-interacting protein 2B (PAIP2B) is a protein from Homo sapiens identified by UniProt accession Q9ULR5, 123 residues long. MolForge cross-references it against 0 known binders and 43 disease associations.

Target properties

Protein name	Polyadenylate-binding protein-interacting protein 2B
UniProt accession	Q9ULR5
Gene	PAIP2B
Organism	Homo sapiens
Length	123 residues
Molecular weight	—
EC numbers	—
Target class	—
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (43)

Diseases linked to this target (Open Targets).

sex hormone-binding globulin measurement · score 0.27
body height · score 0.09
Testicular Germ Cell Tumor · score 0.04
glucuronate measurement · score 0.03
heel bone mineral density · score 0.02
aspartate aminotransferase measurement · score 0.02
mean reticulocyte volume · score 0.02
mean corpuscular volume · score 0.02
mean corpuscular hemoglobin · score 0.02
Acute hepatic failure · score 0.02

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9ULR5-F1	alphafold	PREDICTED	71.33	—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9ULR5.

Amino-acid sequence (123 residues)

MNGSNMANTS PSVKSKEDQG LSGHDEKENP FAEYMWMENE EDFNRQVEEE LQEQDFLDRC FQEMLDEEDQ DWFIPSRDLP QAMGQLQQQL NGLSVSEGHD SEDILSKSNL NPDAKEFIPG EKY

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards

Polyadenylate-binding protein-interacting protein 2B (PAIP2B)