Polyadenylate-binding protein-interacting protein 2B (PAIP2B)
Homo sapiens — UniProt Q9ULR5
Data last refreshed: (UniProt release unknown)
Key facts
Polyadenylate-binding protein-interacting protein 2B (PAIP2B) is a protein from Homo sapiens identified by UniProt accession Q9ULR5, 123 residues long. MolForge cross-references it against 0 known binders and 43 disease associations.
- UniProt accession: Q9ULR5; gene symbol PAIP2B.
- Organism: Homo sapiens.
- Length: 123 amino acids.
- Top disease associations (Open Targets): sex hormone-binding globulin measurement, body height and Testicular Germ Cell Tumor.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Polyadenylate-binding protein-interacting protein 2B |
|---|---|
| UniProt accession | Q9ULR5 |
| Gene | PAIP2B |
| Organism | Homo sapiens |
| Length | 123 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (43)
Diseases linked to this target (Open Targets).
- sex hormone-binding globulin measurement · score 0.27
- body height · score 0.09
- Testicular Germ Cell Tumor · score 0.04
- glucuronate measurement · score 0.03
- heel bone mineral density · score 0.02
- aspartate aminotransferase measurement · score 0.02
- mean reticulocyte volume · score 0.02
- mean corpuscular volume · score 0.02
- mean corpuscular hemoglobin · score 0.02
- Acute hepatic failure · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9ULR5-F1 | alphafold | PREDICTED | 71.33 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9ULR5.
Amino-acid sequence (123 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with PAIP2B?
The strongest Open Targets associations for PAIP2B are sex hormone-binding globulin measurement, body height, Testicular Germ Cell Tumor, glucuronate measurement and heel bone mineral density.
How long is the PAIP2B protein?
The Homo sapiens PAIP2B protein (UniProt Q9ULR5) is 123 amino acids long.
Browse: Targets: P · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9ULR5 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9ULR5 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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