Transmembrane and coiled-coil domain protein 3 (TMCC3)
Homo sapiens — UniProt Q9ULS5
Data last refreshed: (UniProt release unknown)
Key facts
Transmembrane and coiled-coil domain protein 3 (TMCC3) is a protein from Homo sapiens identified by UniProt accession Q9ULS5, 477 residues long. MolForge cross-references it against 0 known binders and 31 disease associations.
- UniProt accession: Q9ULS5; gene symbol TMCC3.
- Organism: Homo sapiens.
- Length: 477 amino acids.
- Top disease associations (Open Targets): hematocrit, hemoglobin measurement and gut microbiome measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Transmembrane and coiled-coil domain protein 3 |
|---|---|
| UniProt accession | Q9ULS5 |
| Gene | TMCC3 |
| Organism | Homo sapiens |
| Length | 477 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (31)
Diseases linked to this target (Open Targets).
- hematocrit · score 0.42
- hemoglobin measurement · score 0.36
- gut microbiome measurement · score 0.31
- mathematical ability · score 0.28
- neuritic plaque measurement · score 0.27
- adolescent idiopathic scoliosis · score 0.20
- metabolite measurement · score 0.18
- myoepithelial tumor · score 0.11
- neoplasm · score 0.07
- cancer · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9ULS5-F1 | alphafold | PREDICTED | 69.86 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9ULS5.
Amino-acid sequence (477 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with TMCC3?
The strongest Open Targets associations for TMCC3 are hematocrit, hemoglobin measurement, gut microbiome measurement, mathematical ability and neuritic plaque measurement.
How long is the TMCC3 protein?
The Homo sapiens TMCC3 protein (UniProt Q9ULS5) is 477 amino acids long.
Browse: Targets: T · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9ULS5 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9ULS5 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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