MYND-type zinc finger-containing chromatin reader ZMYND8 (ZMYND8)
Homo sapiens — UniProt Q9ULU4
Data last refreshed: (UniProt release unknown)
Key facts
MYND-type zinc finger-containing chromatin reader ZMYND8 (ZMYND8) is a protein from Homo sapiens identified by UniProt accession Q9ULU4, 1186 residues long. MolForge cross-references it against 0 known binders and 124 disease associations.
- UniProt accession: Q9ULU4; gene symbol ZMYND8.
- Organism: Homo sapiens.
- Length: 1186 amino acids.
- Top disease associations (Open Targets): mean platelet volume, neuroinflammatory disorder and platelet count.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | MYND-type zinc finger-containing chromatin reader ZMYND8 |
|---|---|
| UniProt accession | Q9ULU4 |
| Gene | ZMYND8 |
| Organism | Homo sapiens |
| Length | 1186 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (124)
Diseases linked to this target (Open Targets).
- mean platelet volume · score 0.46
- neuroinflammatory disorder · score 0.46
- platelet count · score 0.42
- Intellectual disability · score 0.40
- Neurodevelopmental disorder · score 0.39
- neurodegenerative disease · score 0.37
- Abnormality of the face · score 0.37
- Hearing abnormality · score 0.37
- Abnormality of vision · score 0.37
- Delayed speech and language development · score 0.37
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9ULU4-F1 | alphafold | PREDICTED | 58.35 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9ULU4.
Amino-acid sequence (1186 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ZMYND8?
The strongest Open Targets associations for ZMYND8 are mean platelet volume, neuroinflammatory disorder, platelet count, Intellectual disability and Neurodevelopmental disorder.
How long is the ZMYND8 protein?
The Homo sapiens ZMYND8 protein (UniProt Q9ULU4) is 1186 amino acids long.
Browse: Targets: Z · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9ULU4 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9ULU4 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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