Coronin-1C (CORO1C)
Homo sapiens — UniProt Q9ULV4
Data last refreshed: (UniProt release unknown)
Key facts
Coronin-1C (CORO1C) is a protein from Homo sapiens identified by UniProt accession Q9ULV4, 474 residues long. MolForge cross-references it against 0 known binders and 152 disease associations.
- UniProt accession: Q9ULV4; gene symbol CORO1C.
- Organism: Homo sapiens.
- Length: 474 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, reticulocyte measurement and mean platelet volume.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Coronin-1C |
|---|---|
| UniProt accession | Q9ULV4 |
| Gene | CORO1C |
| Organism | Homo sapiens |
| Length | 474 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (152)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.45
- reticulocyte measurement · score 0.36
- mean platelet volume · score 0.36
- brain measurement · score 0.35
- cortical surface area measurement · score 0.33
- cortical thickness · score 0.32
- total blood protein measurement · score 0.32
- Alzheimer disease · score 0.31
- lysosomal storage disease · score 0.31
- Parkinson disease · score 0.31
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9ULV4-F1 | alphafold | PREDICTED | 90.96 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9ULV4.
Amino-acid sequence (474 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CORO1C?
The strongest Open Targets associations for CORO1C are neurodegenerative disease, reticulocyte measurement, mean platelet volume, brain measurement and cortical surface area measurement.
How long is the CORO1C protein?
The Homo sapiens CORO1C protein (UniProt Q9ULV4) is 474 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9ULV4 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9ULV4 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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