Targeting protein for Xklp2 (TPX2)
Homo sapiens — UniProt Q9ULW0
Data last refreshed: (UniProt release unknown)
Key facts
Targeting protein for Xklp2 (TPX2) is a protein from Homo sapiens identified by UniProt accession Q9ULW0, 747 residues long. MolForge cross-references it against 0 known binders and 223 disease associations.
- UniProt accession: Q9ULW0; gene symbol TPX2.
- Organism: Homo sapiens.
- Length: 747 amino acids.
- Top disease associations (Open Targets): erythrocyte count, low grade glioma and red blood cell density measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Targeting protein for Xklp2 |
|---|---|
| UniProt accession | Q9ULW0 |
| Gene | TPX2 |
| Organism | Homo sapiens |
| Length | 747 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (223)
Diseases linked to this target (Open Targets).
- erythrocyte count · score 0.28
- low grade glioma · score 0.27
- red blood cell density measurement · score 0.27
- breast adenocarcinoma · score 0.27
- monocyte count · score 0.26
- ovarian cancer · score 0.26
- brain volume measurement · score 0.26
- glioblastoma multiforme · score 0.25
- mean reticulocyte volume · score 0.24
- putamen volume · score 0.24
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9ULW0-F1 | alphafold | PREDICTED | 63.60 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9ULW0.
Amino-acid sequence (747 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with TPX2?
The strongest Open Targets associations for TPX2 are erythrocyte count, low grade glioma, red blood cell density measurement, breast adenocarcinoma and monocyte count.
How long is the TPX2 protein?
The Homo sapiens TPX2 protein (UniProt Q9ULW0) is 747 amino acids long.
Browse: Targets: T · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9ULW0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9ULW0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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