Ras-related protein Rab-26 (RAB26)
Homo sapiens — UniProt Q9ULW5
Data last refreshed: (UniProt release unknown)
Key facts
Ras-related protein Rab-26 (RAB26) is a protein from Homo sapiens identified by UniProt accession Q9ULW5, 256 residues long. MolForge cross-references it against 0 known binders and 91 disease associations.
- UniProt accession: Q9ULW5; gene symbol RAB26.
- Organism: Homo sapiens.
- Length: 256 amino acids.
- Top disease associations (Open Targets): Parkinson disease, lysosomal storage disease and Alzheimer disease.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Ras-related protein Rab-26 |
|---|---|
| UniProt accession | Q9ULW5 |
| Gene | RAB26 |
| Organism | Homo sapiens |
| Length | 256 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (91)
Diseases linked to this target (Open Targets).
- Parkinson disease · score 0.27
- lysosomal storage disease · score 0.27
- Alzheimer disease · score 0.27
- multiple sclerosis · score 0.27
- neurodegenerative disease · score 0.27
- C-reactive protein measurement · score 0.14
- BMI-adjusted waist-hip ratio · score 0.13
- non-small cell lung carcinoma · score 0.09
- waist-hip ratio · score 0.08
- fat body mass · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9ULW5-F1 | alphafold | PREDICTED | 78.32 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9ULW5.
Amino-acid sequence (256 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with RAB26?
The strongest Open Targets associations for RAB26 are Parkinson disease, lysosomal storage disease, Alzheimer disease, multiple sclerosis and neurodegenerative disease.
How long is the RAB26 protein?
The Homo sapiens RAB26 protein (UniProt Q9ULW5) is 256 amino acids long.
Browse: Targets: R · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9ULW5 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9ULW5 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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