Nucleosome assembly protein 1-like 2 (NAP1L2)
Homo sapiens — UniProt Q9ULW6
Data last refreshed: (UniProt release unknown)
Key facts
Nucleosome assembly protein 1-like 2 (NAP1L2) is a protein from Homo sapiens identified by UniProt accession Q9ULW6, 460 residues long. MolForge cross-references it against 0 known binders and 45 disease associations.
- UniProt accession: Q9ULW6; gene symbol NAP1L2.
- Organism: Homo sapiens.
- Length: 460 amino acids.
- Top disease associations (Open Targets): Abnormality of neuronal migration, glioblastoma multiforme and large cell medulloblastoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Nucleosome assembly protein 1-like 2 |
|---|---|
| UniProt accession | Q9ULW6 |
| Gene | NAP1L2 |
| Organism | Homo sapiens |
| Length | 460 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (45)
Diseases linked to this target (Open Targets).
- Abnormality of neuronal migration · score 0.11
- glioblastoma multiforme · score 0.04
- large cell medulloblastoma · score 0.03
- colorectal adenocarcinoma · score 0.03
- Tetralogy of Fallot · score 0.03
- osteoporosis · score 0.02
- atypical teratoid rhabdoid tumor · score 0.02
- breast carcinoma · score 0.02
- ovarian carcinoma · score 0.02
- inflammatory bowel disease · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9ULW6-F1 | alphafold | PREDICTED | 66.97 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9ULW6.
Amino-acid sequence (460 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with NAP1L2?
The strongest Open Targets associations for NAP1L2 are Abnormality of neuronal migration, glioblastoma multiforme, large cell medulloblastoma, colorectal adenocarcinoma and Tetralogy of Fallot.
How long is the NAP1L2 protein?
The Homo sapiens NAP1L2 protein (UniProt Q9ULW6) is 460 amino acids long.
Browse: Targets: N · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9ULW6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9ULW6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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