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RNA-binding protein NOB1 (NOB1)

Homo sapiens — UniProt Q9ULX3

Gene: NOB1Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

RNA-binding protein NOB1 (NOB1) is a protein from Homo sapiens identified by UniProt accession Q9ULX3, 412 residues long. MolForge cross-references it against 0 known binders and 95 disease associations.

  • UniProt accession: Q9ULX3; gene symbol NOB1.
  • Organism: Homo sapiens.
  • Length: 412 amino acids.
  • Top disease associations (Open Targets): pulse pressure measurement, neurodegenerative disease and mathematical ability.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameRNA-binding protein NOB1
UniProt accessionQ9ULX3
GeneNOB1
OrganismHomo sapiens
Length412 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (95)

Diseases linked to this target (Open Targets).

  • pulse pressure measurement · score 0.23
  • neurodegenerative disease · score 0.19
  • mathematical ability · score 0.16
  • smoking behavior · score 0.14
  • asthma · score 0.11
  • cystatin C measurement · score 0.11
  • vital capacity · score 0.10
  • forced expiratory volume · score 0.10
  • triglyceride measurement · score 0.10
  • age at menarche · score 0.09

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q9ULX3-F1alphafoldPREDICTED72.62—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9ULX3.

Amino-acid sequence (412 residues)

MAPVEHVVAD AGAFLRHAAL QDIGKNIYTI REVVTEIRDK ATRRRLAVLP YELRFKEPLP EYVRLVTEFS KKTGDYPSLS ATDIQVLALT YQLEAEFVGV SHLKQEPQKV KVSSSIQHPE TPLHISGFHL PYKPKPPQET EKGHSACEPE NLEFSSFMFW RNPLPNIDHE LQELLIDRGE DVPSEEEEEE ENGFEDRKDD SDDDGGGWIT PSNIKQIQQE LEQCDVPEDV RVGCLTTDFA MQNVLLQMGL HVLAVNGMLI REARSYILRC HGCFKTTSDM SRVFCSHCGN KTLKKVSVTV SDDGTLHMHF SRNPKVLNPR GLRYSLPTPK GGKYAINPHL TEDQRFPQLR LSQKARQKTN VFAPDYIAGV SPFVENDISS RSATLQVRDS TLGAGRRRLN PNASRKKFVK KR

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with NOB1?

The strongest Open Targets associations for NOB1 are pulse pressure measurement, neurodegenerative disease, mathematical ability, smoking behavior and asthma.

How long is the NOB1 protein?

The Homo sapiens NOB1 protein (UniProt Q9ULX3) is 412 amino acids long.

Browse: Targets: N · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ9ULX3
GeneNOB1
OrganismHomo sapiens
Length412
Binders0
Diseases95
View on UniProt