RING finger protein 112 (RNF112)
Homo sapiens — UniProt Q9ULX5
Data last refreshed: (UniProt release unknown)
Key facts
RING finger protein 112 (RNF112) is a protein from Homo sapiens identified by UniProt accession Q9ULX5, 631 residues long. MolForge cross-references it against 0 known binders and 62 disease associations.
- UniProt accession: Q9ULX5; gene symbol RNF112.
- Organism: Homo sapiens.
- Length: 631 amino acids.
- Top disease associations (Open Targets): self reported educational attainment, attention deficit hyperactivity disorder and glioblastoma multiforme.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | RING finger protein 112 |
|---|---|
| UniProt accession | Q9ULX5 |
| Gene | RNF112 |
| Organism | Homo sapiens |
| Length | 631 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (62)
Diseases linked to this target (Open Targets).
- self reported educational attainment · score 0.10
- attention deficit hyperactivity disorder · score 0.09
- glioblastoma multiforme · score 0.07
- lymphocyte count · score 0.07
- attention deficit-hyperactivity disorder 8 · score 0.07
- schizophrenia 15 · score 0.07
- lifestyle measurement · score 0.07
- Asperger syndrome · score 0.06
- mathematical ability · score 0.06
- Phelan-McDermid syndrome · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9ULX5-F1 | alphafold | PREDICTED | 68.68 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9ULX5.
Amino-acid sequence (631 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with RNF112?
The strongest Open Targets associations for RNF112 are self reported educational attainment, attention deficit hyperactivity disorder, glioblastoma multiforme, lymphocyte count and attention deficit-hyperactivity disorder 8.
How long is the RNF112 protein?
The Homo sapiens RNF112 protein (UniProt Q9ULX5) is 631 amino acids long.
Browse: Targets: R · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9ULX5 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9ULX5 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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