Transcription factor MafF (MAFF)
Homo sapiens — UniProt Q9ULX9
Data last refreshed: (UniProt release unknown)
Key facts
Transcription factor MafF (MAFF) is a protein from Homo sapiens identified by UniProt accession Q9ULX9, 164 residues long. MolForge cross-references it against 0 known binders and 132 disease associations.
- UniProt accession: Q9ULX9; gene symbol MAFF.
- Organism: Homo sapiens.
- Length: 164 amino acids.
- Top disease associations (Open Targets): triglyceride measurement, body fat percentage and high density lipoprotein cholesterol measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Transcription factor MafF |
|---|---|
| UniProt accession | Q9ULX9 |
| Gene | MAFF |
| Organism | Homo sapiens |
| Length | 164 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (132)
Diseases linked to this target (Open Targets).
- triglyceride measurement · score 0.21
- body fat percentage · score 0.21
- high density lipoprotein cholesterol measurement · score 0.21
- neurodegenerative disease · score 0.20
- glomerular filtration rate · score 0.20
- serum alanine aminotransferase measurement · score 0.20
- body height · score 0.18
- sex hormone-binding globulin measurement · score 0.17
- alcohol drinking · score 0.17
- nevus count · score 0.16
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9ULX9-F1 | alphafold | PREDICTED | 81.97 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9ULX9.
Amino-acid sequence (164 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with MAFF?
The strongest Open Targets associations for MAFF are triglyceride measurement, body fat percentage, high density lipoprotein cholesterol measurement, neurodegenerative disease and glomerular filtration rate.
How long is the MAFF protein?
The Homo sapiens MAFF protein (UniProt Q9ULX9) is 164 amino acids long.
Browse: Targets: M · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9ULX9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9ULX9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.