C-type lectin domain family 4 member E (CLEC4E)
Homo sapiens — UniProt Q9ULY5
Data last refreshed: (UniProt release unknown)
Key facts
C-type lectin domain family 4 member E (CLEC4E) is a protein from Homo sapiens identified by UniProt accession Q9ULY5, 219 residues long. MolForge cross-references it against 0 known binders and 287 disease associations.
- UniProt accession: Q9ULY5; gene symbol CLEC4E.
- Organism: Homo sapiens.
- Length: 219 amino acids.
- Top disease associations (Open Targets): squamous cell lung carcinoma, glioblastoma multiforme and breast adenocarcinoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | C-type lectin domain family 4 member E |
|---|---|
| UniProt accession | Q9ULY5 |
| Gene | CLEC4E |
| Organism | Homo sapiens |
| Length | 219 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (287)
Diseases linked to this target (Open Targets).
- squamous cell lung carcinoma · score 0.18
- glioblastoma multiforme · score 0.17
- breast adenocarcinoma · score 0.16
- head and neck squamous cell carcinoma · score 0.12
- infection · score 0.09
- infect · score 0.09
- psoriasis · score 0.09
- experimental autoimmune encephalomyelitis · score 0.08
- isolated agammaglobulinemia · score 0.07
- acute kidney failure · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9ULY5-F1 | alphafold | PREDICTED | 85.18 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9ULY5.
Amino-acid sequence (219 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CLEC4E?
The strongest Open Targets associations for CLEC4E are squamous cell lung carcinoma, glioblastoma multiforme, breast adenocarcinoma, head and neck squamous cell carcinoma and infection.
How long is the CLEC4E protein?
The Homo sapiens CLEC4E protein (UniProt Q9ULY5) is 219 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9ULY5 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9ULY5 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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