Matrix metalloproteinase-17 (MMP17)
Homo sapiens — UniProt Q9ULZ9
Data last refreshed: (UniProt release unknown)
Key facts
Matrix metalloproteinase-17 (MMP17) is a protein from Homo sapiens identified by UniProt accession Q9ULZ9, 603 residues long. MolForge cross-references it against 0 known binders and 84 disease associations.
- UniProt accession: Q9ULZ9; gene symbol MMP17.
- Organism: Homo sapiens.
- Length: 603 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, serum gamma-glutamyl transferase measurement and mathematical ability.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Matrix metalloproteinase-17 |
|---|---|
| UniProt accession | Q9ULZ9 |
| Gene | MMP17 |
| Organism | Homo sapiens |
| Length | 603 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (84)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.43
- serum gamma-glutamyl transferase measurement · score 0.38
- mathematical ability · score 0.34
- eosinophil count · score 0.31
- lung adenocarcinoma · score 0.18
- self reported educational attainment · score 0.18
- cutaneous melanoma · score 0.15
- glioblastoma multiforme · score 0.10
- nephronophthisis · score 0.07
- Senior-Loken syndrome · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9ULZ9-F1 | alphafold | PREDICTED | 76.30 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9ULZ9.
Amino-acid sequence (603 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with MMP17?
The strongest Open Targets associations for MMP17 are neurodegenerative disease, serum gamma-glutamyl transferase measurement, mathematical ability, eosinophil count and lung adenocarcinoma.
How long is the MMP17 protein?
The Homo sapiens MMP17 protein (UniProt Q9ULZ9) is 603 amino acids long.
Browse: Targets: M · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9ULZ9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9ULZ9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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