Intercellular adhesion molecule 5 (ICAM5)
Homo sapiens — UniProt Q9UMF0
Data last refreshed: (UniProt release unknown)
Key facts
Intercellular adhesion molecule 5 (ICAM5) is a protein from Homo sapiens identified by UniProt accession Q9UMF0, 924 residues long. MolForge cross-references it against 0 known binders and 98 disease associations.
- UniProt accession: Q9UMF0; gene symbol ICAM5.
- Organism: Homo sapiens.
- Length: 924 amino acids.
- Top disease associations (Open Targets): lymphocyte count, lymphocyte percentage of leukocytes and protein measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Intercellular adhesion molecule 5 |
|---|---|
| UniProt accession | Q9UMF0 |
| Gene | ICAM5 |
| Organism | Homo sapiens |
| Length | 924 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (98)
Diseases linked to this target (Open Targets).
- lymphocyte count · score 0.30
- lymphocyte percentage of leukocytes · score 0.29
- protein measurement · score 0.29
- blood protein measurement · score 0.28
- sex hormone-binding globulin measurement · score 0.25
- insulin like growth factor measurement · score 0.23
- breast adenocarcinoma · score 0.22
- lymphocyte:monocyte ratio · score 0.22
- Eczematoid dermatitis · score 0.22
- intercellular adhesion molecule 5 measurement · score 0.22
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9UMF0-F1 | alphafold | PREDICTED | 80.10 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9UMF0.
Amino-acid sequence (924 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ICAM5?
The strongest Open Targets associations for ICAM5 are lymphocyte count, lymphocyte percentage of leukocytes, protein measurement, blood protein measurement and sex hormone-binding globulin measurement.
How long is the ICAM5 protein?
The Homo sapiens ICAM5 protein (UniProt Q9UMF0) is 924 amino acids long.
Browse: Targets: I · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9UMF0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9UMF0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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