Calpain-11 (CAPN11)
Homo sapiens — UniProt Q9UMQ6
Data last refreshed: (UniProt release unknown)
Key facts
Calpain-11 (CAPN11) is a protein from Homo sapiens identified by UniProt accession Q9UMQ6, 739 residues long. MolForge cross-references it against 0 known binders and 67 disease associations.
- UniProt accession: Q9UMQ6; gene symbol CAPN11.
- Organism: Homo sapiens.
- Length: 739 amino acids.
- Top disease associations (Open Targets): breast adenocarcinoma, interleukin 12 measurement and vascular endothelial growth factor measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Calpain-11 |
|---|---|
| UniProt accession | Q9UMQ6 |
| Gene | CAPN11 |
| Organism | Homo sapiens |
| Length | 739 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (67)
Diseases linked to this target (Open Targets).
- breast adenocarcinoma · score 0.22
- interleukin 12 measurement · score 0.22
- vascular endothelial growth factor measurement · score 0.20
- Red cell distribution width · score 0.14
- vascular endothelial growth factor A measurement · score 0.12
- genetic disorder · score 0.12
- interleukin 10 measurement · score 0.11
- MODY · score 0.11
- hemoglobin measurement · score 0.11
- fibroblast growth factor basic measurement · score 0.10
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9UMQ6-F1 | alphafold | PREDICTED | 86.75 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9UMQ6.
Amino-acid sequence (739 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CAPN11?
The strongest Open Targets associations for CAPN11 are breast adenocarcinoma, interleukin 12 measurement, vascular endothelial growth factor measurement, Red cell distribution width and vascular endothelial growth factor A measurement.
How long is the CAPN11 protein?
The Homo sapiens CAPN11 protein (UniProt Q9UMQ6) is 739 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9UMQ6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9UMQ6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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