Ubiquilin-1 (UBQLN1)
Homo sapiens — UniProt Q9UMX0
Data last refreshed: (UniProt release unknown)
Key facts
Ubiquilin-1 (UBQLN1) is a protein from Homo sapiens identified by UniProt accession Q9UMX0, 589 residues long. MolForge cross-references it against 0 known binders and 84 disease associations.
- UniProt accession: Q9UMX0; gene symbol UBQLN1.
- Organism: Homo sapiens.
- Length: 589 amino acids.
- Top disease associations (Open Targets): Abnormal brain morphology, apolipoprotein A 1 measurement and IGF-1 measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Ubiquilin-1 |
|---|---|
| UniProt accession | Q9UMX0 |
| Gene | UBQLN1 |
| Organism | Homo sapiens |
| Length | 589 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (84)
Diseases linked to this target (Open Targets).
- Abnormal brain morphology · score 0.27
- apolipoprotein A 1 measurement · score 0.26
- IGF-1 measurement · score 0.26
- bilirubin measurement · score 0.26
- Abnormality of refraction · score 0.21
- DNA methylation · score 0.21
- lung adenocarcinoma · score 0.19
- age at first sexual intercourse measurement · score 0.09
- cancer · score 0.07
- non-small cell lung carcinoma · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9UMX0-F1 | alphafold | PREDICTED | 62.91 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9UMX0.
Amino-acid sequence (589 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with UBQLN1?
The strongest Open Targets associations for UBQLN1 are Abnormal brain morphology, apolipoprotein A 1 measurement, IGF-1 measurement, bilirubin measurement and Abnormality of refraction.
How long is the UBQLN1 protein?
The Homo sapiens UBQLN1 protein (UniProt Q9UMX0) is 589 amino acids long.
Browse: Targets: U · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9UMX0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9UMX0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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