Bcl-2-related ovarian killer protein (BOK)
Homo sapiens — UniProt Q9UMX3
Data last refreshed: (UniProt release unknown)
Key facts
Bcl-2-related ovarian killer protein (BOK) is a protein from Homo sapiens identified by UniProt accession Q9UMX3, 212 residues long. MolForge cross-references it against 0 known binders and 113 disease associations.
- UniProt accession: Q9UMX3; gene symbol BOK.
- Organism: Homo sapiens.
- Length: 212 amino acids.
- Top disease associations (Open Targets): body height, lean body mass and vital capacity.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Bcl-2-related ovarian killer protein |
|---|---|
| UniProt accession | Q9UMX3 |
| Gene | BOK |
| Organism | Homo sapiens |
| Length | 212 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (113)
Diseases linked to this target (Open Targets).
- body height · score 0.41
- lean body mass · score 0.40
- vital capacity · score 0.39
- forced expiratory volume · score 0.38
- body weight · score 0.35
- fat body mass · score 0.31
- appendicular lean mass · score 0.28
- sitting height measurement · score 0.28
- erythrocyte count · score 0.27
- peak expiratory flow · score 0.27
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9UMX3-F1 | alphafold | PREDICTED | 83.47 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9UMX3.
Amino-acid sequence (212 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with BOK?
The strongest Open Targets associations for BOK are body height, lean body mass, vital capacity, forced expiratory volume and body weight.
How long is the BOK protein?
The Homo sapiens BOK protein (UniProt Q9UMX3) is 212 amino acids long.
Browse: Targets: B · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9UMX3 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9UMX3 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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