Membrane-associated transporter protein (SLC45A2)
Homo sapiens — UniProt Q9UMX9
Data last refreshed: (UniProt release unknown)
Key facts
Membrane-associated transporter protein (SLC45A2) is a protein from Homo sapiens identified by UniProt accession Q9UMX9, 530 residues long. MolForge cross-references it against 0 known binders and 214 disease associations.
- UniProt accession: Q9UMX9; gene symbol SLC45A2.
- Organism: Homo sapiens.
- Length: 530 amino acids.
- Target class: Transporter.
- Top disease associations (Open Targets): oculocutaneous albinism type 4, hair colour measurement and skin pigmentation.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Membrane-associated transporter protein |
|---|---|
| UniProt accession | Q9UMX9 |
| Gene | SLC45A2 |
| Organism | Homo sapiens |
| Length | 530 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | Transporter (inferred from UniProt keywords / EC) |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (214)
Diseases linked to this target (Open Targets).
- oculocutaneous albinism type 4 · score 0.84
- hair colour measurement · score 0.70
- skin pigmentation · score 0.70
- skin pigmentation measurement · score 0.69
- oculocutaneous albinism · score 0.61
- oculocutaneous albinism type 6 · score 0.52
- hair color · score 0.50
- cutaneous melanoma · score 0.45
- suntan · score 0.44
- hair morphology measurement · score 0.44
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9UMX9-F1 | alphafold | PREDICTED | 77.73 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9UMX9.
Amino-acid sequence (530 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SLC45A2?
The strongest Open Targets associations for SLC45A2 are oculocutaneous albinism type 4, hair colour measurement, skin pigmentation, skin pigmentation measurement and oculocutaneous albinism.
How long is the SLC45A2 protein?
The Homo sapiens SLC45A2 protein (UniProt Q9UMX9) is 530 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9UMX9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9UMX9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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