Protein ATP1B4 (ATP1B4)
Homo sapiens — UniProt Q9UN42
Data last refreshed: (UniProt release unknown)
Key facts
Protein ATP1B4 (ATP1B4) is a protein from Homo sapiens identified by UniProt accession Q9UN42, 357 residues long. MolForge cross-references it against 0 known binders and 11 disease associations.
- UniProt accession: Q9UN42; gene symbol ATP1B4.
- Organism: Homo sapiens.
- Length: 357 amino acids.
- Top disease associations (Open Targets): acute myeloid leukemia, alcohol-related disorders and mental or behavioural disorder.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Protein ATP1B4 |
|---|---|
| UniProt accession | Q9UN42 |
| Gene | ATP1B4 |
| Organism | Homo sapiens |
| Length | 357 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (11)
Diseases linked to this target (Open Targets).
- acute myeloid leukemia · score 0.18
- alcohol-related disorders · score 0.02
- mental or behavioural disorder · score 0.02
- Glycogen Storage Disease Type 2b · score 0.01
- Parkinson disease · score 0.01
- atrial fibrillation · score 0.01
- gonorrhea · score 0.01
- central nervous system cancer · score 0.00
- oral squamous cell carcinoma · score 0.00
- Duchenne muscular dystrophy · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9UN42-F1 | alphafold | PREDICTED | 81.77 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9UN42.
Amino-acid sequence (357 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ATP1B4?
The strongest Open Targets associations for ATP1B4 are acute myeloid leukemia, alcohol-related disorders, mental or behavioural disorder, Glycogen Storage Disease Type 2b and Parkinson disease.
How long is the ATP1B4 protein?
The Homo sapiens ATP1B4 protein (UniProt Q9UN42) is 357 amino acids long.
Browse: Targets: A · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9UN42 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9UN42 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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