Sorting nexin-7 (SNX7)

About Sorting nexin-7

Sorting nexin-7 (SNX7) is a protein from Homo sapiens identified by UniProt accession Q9UNH6, 387 residues long. MolForge cross-references it against 0 known binders and 29 disease associations.

Target properties

Protein name	Sorting nexin-7
UniProt accession	Q9UNH6
Gene	SNX7
Organism	Homo sapiens
Length	387 residues
Molecular weight	—
EC numbers	—
Target class	—
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (29)

Diseases linked to this target (Open Targets).

mathematical ability · score 0.39
insulin measurement · score 0.30
leukocyte count · score 0.27
appendicular lean mass · score 0.20
self reported educational attainment · score 0.10
hepatocellular carcinoma · score 0.05
smoking status measurement · score 0.03
ovarian carcinoma · score 0.01
Duchenne muscular dystrophy · score 0.01
psoriatic arthritis · score 0.01

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9UNH6-F1	alphafold	PREDICTED	85.78	—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9UNH6.

Amino-acid sequence (387 residues)

MDMNSFSPMM PTSPLSMINQ IKFEDEPDLK DLFITVDEPE SHVTTIETFI TYRIITKTSR GEFDSSEFEV RRRYQDFLWL KGKLEEAHPT LIIPPLPEKF IVKGMVERFN DDFIETRRKA LHKFLNRIAD HPTLTFNEDF KIFLTAQAWE LSSHKKQGPG LLSRMGQTVR AVASSMRGVK NRPEEFMEMN NFIELFSQKI NLIDKISQRI YKEEREYFDE MKEYGPIHIL WSASEEDLVD TLKDVASCID RCCKATEKRM SGLSEALLPV VHEYVLYSEM LMGVMKRRDQ IQAELDSKVE VLTYKKADTD LLPEEIGKLE DKVECANNAL KADWERWKQN MQNDIKLAFT DMAEENIHYY EQCLATWESF LTSQTNLHLE EASEDKP

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards