Chymotrypsin-like elastase family member 1 (CELA1)
Homo sapiens — UniProt Q9UNI1
Data last refreshed: (UniProt release unknown)
Key facts
Chymotrypsin-like elastase family member 1 (CELA1) is a protein from Homo sapiens identified by UniProt accession Q9UNI1, 258 residues long. MolForge cross-references it against 1 known binders and 40 disease associations.
- UniProt accession: Q9UNI1; gene symbol CELA1.
- Organism: Homo sapiens.
- Length: 258 amino acids.
- Top disease associations (Open Targets): refractive error measurement, basophil count and lymphocyte count.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Chymotrypsin-like elastase family member 1 |
|---|---|
| UniProt accession | Q9UNI1 |
| Gene | CELA1 |
| Organism | Homo sapiens |
| Length | 258 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (40)
Diseases linked to this target (Open Targets).
- refractive error measurement · score 0.27
- basophil count · score 0.25
- lymphocyte count · score 0.25
- basophil percentage of leukocytes · score 0.17
- mean platelet volume · score 0.16
- neutrophil count · score 0.14
- platelet count · score 0.12
- platelet component distribution width · score 0.11
- emphysema · score 0.09
- myeloid white cell count · score 0.09
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9UNI1-F1 | alphafold | PREDICTED | 92.56 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9UNI1.
Amino-acid sequence (258 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CELA1?
The strongest Open Targets associations for CELA1 are refractive error measurement, basophil count, lymphocyte count, basophil percentage of leukocytes and mean platelet volume.
How long is the CELA1 protein?
The Homo sapiens CELA1 protein (UniProt Q9UNI1) is 258 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9UNI1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9UNI1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.