Dual specificity protein phosphatase 12 (DUSP12)
Homo sapiens — UniProt Q9UNI6
Data last refreshed: (UniProt release unknown)
Key facts
Dual specificity protein phosphatase 12 (DUSP12) is a protein from Homo sapiens identified by UniProt accession Q9UNI6, 340 residues long. MolForge cross-references it against 0 known binders and 57 disease associations.
- UniProt accession: Q9UNI6; gene symbol DUSP12.
- Organism: Homo sapiens.
- Length: 340 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, total blood protein measurement and neuroinflammatory disorder.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Dual specificity protein phosphatase 12 |
|---|---|
| UniProt accession | Q9UNI6 |
| Gene | DUSP12 |
| Organism | Homo sapiens |
| Length | 340 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (57)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.49
- total blood protein measurement · score 0.23
- neuroinflammatory disorder · score 0.17
- blood protein measurement · score 0.14
- serum IgG measurement · score 0.14
- serum non-albumin protein measurement · score 0.14
- albumin:globulin ratio measurement · score 0.14
- alkaline phosphatase measurement · score 0.12
- aspartate aminotransferase measurement · score 0.10
- serum alanine aminotransferase measurement · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9UNI6-F1 | alphafold | PREDICTED | 85.21 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9UNI6.
Amino-acid sequence (340 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with DUSP12?
The strongest Open Targets associations for DUSP12 are neurodegenerative disease, total blood protein measurement, neuroinflammatory disorder, blood protein measurement and serum IgG measurement.
How long is the DUSP12 protein?
The Homo sapiens DUSP12 protein (UniProt Q9UNI6) is 340 amino acids long.
Browse: Targets: D · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9UNI6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9UNI6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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