Inhibitor of growth protein 4 (ING4)
Homo sapiens — UniProt Q9UNL4
Data last refreshed: (UniProt release unknown)
Key facts
Inhibitor of growth protein 4 (ING4) is a protein from Homo sapiens identified by UniProt accession Q9UNL4, 249 residues long. MolForge cross-references it against 0 known binders and 99 disease associations.
- UniProt accession: Q9UNL4; gene symbol ING4.
- Organism: Homo sapiens.
- Length: 249 amino acids.
- Top disease associations (Open Targets): breast adenocarcinoma, neoplasm and prostate cancer.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Inhibitor of growth protein 4 |
|---|---|
| UniProt accession | Q9UNL4 |
| Gene | ING4 |
| Organism | Homo sapiens |
| Length | 249 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (99)
Diseases linked to this target (Open Targets).
- breast adenocarcinoma · score 0.22
- neoplasm · score 0.11
- prostate cancer · score 0.11
- Familial prostate cancer · score 0.11
- prostate carcinoma · score 0.11
- breast cancer · score 0.10
- hepatocellular carcinoma · score 0.10
- melanoma · score 0.09
- renal cell carcinoma · score 0.08
- colorectal carcinoma · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9UNL4-F1 | alphafold | PREDICTED | 76.53 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9UNL4.
Amino-acid sequence (249 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ING4?
The strongest Open Targets associations for ING4 are breast adenocarcinoma, neoplasm, prostate cancer, Familial prostate cancer and prostate carcinoma.
How long is the ING4 protein?
The Homo sapiens ING4 protein (UniProt Q9UNL4) is 249 amino acids long.
Browse: Targets: I · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9UNL4 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9UNL4 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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