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26S proteasome non-ATPase regulatory subunit 13 (PSMD13)

Homo sapiens — UniProt Q9UNM6

Gene: PSMD13Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

26S proteasome non-ATPase regulatory subunit 13 (PSMD13) is a protein from Homo sapiens identified by UniProt accession Q9UNM6, 376 residues long. MolForge cross-references it against 0 known binders and 57 disease associations.

  • UniProt accession: Q9UNM6; gene symbol PSMD13.
  • Organism: Homo sapiens.
  • Length: 376 amino acids.
  • Top disease associations (Open Targets): neurodegenerative disease, HIV infection and breast adenocarcinoma.
  • 3D structure: AlphaFold model available.

Target properties

Protein name26S proteasome non-ATPase regulatory subunit 13
UniProt accessionQ9UNM6
GenePSMD13
OrganismHomo sapiens
Length376 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (57)

Diseases linked to this target (Open Targets).

  • neurodegenerative disease · score 0.52
  • HIV infection · score 0.46
  • breast adenocarcinoma · score 0.30
  • ovarian cancer · score 0.29
  • lung adenocarcinoma · score 0.28
  • squamous cell lung carcinoma · score 0.28
  • HbA1c measurement · score 0.24
  • mean platelet volume · score 0.24
  • platelet count · score 0.22
  • age at menarche · score 0.19

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q9UNM6-F1alphafoldPREDICTED70.76—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9UNM6.

Amino-acid sequence (376 residues)

MKDVPGFLQQ SQNSGPGQPA VWHRLEELYT KKLWHQLTLQ VLDFVQDPCF AQGDGLIKLY ENFISEFEHR VNPLSLVEII LHVVRQMTDP NVALTFLEKT REKVKSSDEA VILCKTAIGA LKLNIGDLQV TKETIEDVEE MLNNLPGVTS VHSRFYDLSS KYYQTIGNHA SYYKDALRFL GCVDIKDLPV SEQQERAFTL GLAGLLGEGV FNFGELLMHP VLESLRNTDR QWLIDTLYAF NSGNVERFQT LKTAWGQQPD LAANEAQLLR KIQLLCLMEM TFTRPANHRQ LTFEEIAKSA KITVNEVELL VMKALSVGLV KGSIDEVDKR VHMTWVQPRV LDLQQIKGMK DRLEFWCTDV KSMEMLVEHQ AHDILT

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with PSMD13?

The strongest Open Targets associations for PSMD13 are neurodegenerative disease, HIV infection, breast adenocarcinoma, ovarian cancer and lung adenocarcinoma.

How long is the PSMD13 protein?

The Homo sapiens PSMD13 protein (UniProt Q9UNM6) is 376 amino acids long.

Browse: Targets: P · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ9UNM6
GenePSMD13
OrganismHomo sapiens
Length376
Binders0
Diseases57
View on UniProt