FAS-associated factor 1 (FAF1)
Homo sapiens — UniProt Q9UNN5
Data last refreshed: (UniProt release unknown)
Key facts
FAS-associated factor 1 (FAF1) is a protein from Homo sapiens identified by UniProt accession Q9UNN5, 650 residues long. MolForge cross-references it against 0 known binders and 254 disease associations.
- UniProt accession: Q9UNN5; gene symbol FAF1.
- Organism: Homo sapiens.
- Length: 650 amino acids.
- Top disease associations (Open Targets): cataract, body height and triglyceride measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | FAS-associated factor 1 |
|---|---|
| UniProt accession | Q9UNN5 |
| Gene | FAF1 |
| Organism | Homo sapiens |
| Length | 650 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (254)
Diseases linked to this target (Open Targets).
- cataract · score 0.26
- body height · score 0.25
- triglyceride measurement · score 0.24
- type 2 diabetes mellitus · score 0.24
- sex hormone-binding globulin measurement · score 0.24
- Ischemic stroke · score 0.23
- large artery stroke · score 0.23
- peak expiratory flow · score 0.23
- HbA1c measurement · score 0.22
- lean body mass · score 0.22
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9UNN5-F1 | alphafold | PREDICTED | 77.02 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9UNN5.
Amino-acid sequence (650 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with FAF1?
The strongest Open Targets associations for FAF1 are cataract, body height, triglyceride measurement, type 2 diabetes mellitus and sex hormone-binding globulin measurement.
How long is the FAF1 protein?
The Homo sapiens FAF1 protein (UniProt Q9UNN5) is 650 amino acids long.
Browse: Targets: F · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9UNN5 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9UNN5 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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