Multiple inositol polyphosphate phosphatase 1 (MINPP1)
Homo sapiens — UniProt Q9UNW1
Data last refreshed: (UniProt release unknown)
Key facts
Multiple inositol polyphosphate phosphatase 1 (MINPP1) is a protein from Homo sapiens identified by UniProt accession Q9UNW1, 487 residues long. MolForge cross-references it against 0 known binders and 40 disease associations.
- UniProt accession: Q9UNW1; gene symbol MINPP1.
- Organism: Homo sapiens.
- Length: 487 amino acids.
- Top disease associations (Open Targets): pontocerebellar hypoplasia, follicular thyroid carcinoma and neurodegenerative disease.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Multiple inositol polyphosphate phosphatase 1 |
|---|---|
| UniProt accession | Q9UNW1 |
| Gene | MINPP1 |
| Organism | Homo sapiens |
| Length | 487 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (40)
Diseases linked to this target (Open Targets).
- pontocerebellar hypoplasia · score 0.61
- follicular thyroid carcinoma · score 0.58
- neurodegenerative disease · score 0.42
- pontocerebellar hypoplasia type 7 · score 0.37
- Non-syndromic pontocerebellar hypoplasia · score 0.34
- blood protein measurement · score 0.34
- follicular thyroid adenoma · score 0.33
- hepatocellular carcinoma · score 0.08
- neoplasm · score 0.03
- glioblastoma · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9UNW1-F1 | alphafold | PREDICTED | 89.52 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9UNW1.
Amino-acid sequence (487 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with MINPP1?
The strongest Open Targets associations for MINPP1 are pontocerebellar hypoplasia, follicular thyroid carcinoma, neurodegenerative disease, pontocerebellar hypoplasia type 7 and Non-syndromic pontocerebellar hypoplasia.
How long is the MINPP1 protein?
The Homo sapiens MINPP1 protein (UniProt Q9UNW1) is 487 amino acids long.
Browse: Targets: M · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9UNW1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9UNW1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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