Exocyst complex component 7 (EXOC7)
Homo sapiens — UniProt Q9UPT5
Data last refreshed: (UniProt release unknown)
Key facts
Exocyst complex component 7 (EXOC7) is a protein from Homo sapiens identified by UniProt accession Q9UPT5, 735 residues long. MolForge cross-references it against 0 known binders and 50 disease associations.
- UniProt accession: Q9UPT5; gene symbol EXOC7.
- Organism: Homo sapiens.
- Length: 735 amino acids.
- Top disease associations (Open Targets): neurodevelopmental disorder with seizures and brain atrophy, neurodegenerative disease and Microcephaly.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Exocyst complex component 7 |
|---|---|
| UniProt accession | Q9UPT5 |
| Gene | EXOC7 |
| Organism | Homo sapiens |
| Length | 735 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (50)
Diseases linked to this target (Open Targets).
- neurodevelopmental disorder with seizures and brain atrophy · score 0.58
- neurodegenerative disease · score 0.53
- Microcephaly · score 0.26
- Brain atrophy · score 0.26
- Global developmental delay · score 0.26
- Seizure · score 0.25
- microcephaly · score 0.25
- genetic disorder · score 0.19
- endometrial cancer · score 0.18
- complex neurodevelopmental disorder · score 0.18
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9UPT5-F1 | alphafold | PREDICTED | 82.60 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9UPT5.
Amino-acid sequence (735 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with EXOC7?
The strongest Open Targets associations for EXOC7 are neurodevelopmental disorder with seizures and brain atrophy, neurodegenerative disease, Microcephaly, Brain atrophy and Global developmental delay.
How long is the EXOC7 protein?
The Homo sapiens EXOC7 protein (UniProt Q9UPT5) is 735 amino acids long.
Browse: Targets: E · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9UPT5 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9UPT5 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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