Protein Smaug homolog 1 (SAMD4A)
Homo sapiens — UniProt Q9UPU9
Data last refreshed: (UniProt release unknown)
Key facts
Protein Smaug homolog 1 (SAMD4A) is a protein from Homo sapiens identified by UniProt accession Q9UPU9, 718 residues long. MolForge cross-references it against 0 known binders and 105 disease associations.
- UniProt accession: Q9UPU9; gene symbol SAMD4A.
- Organism: Homo sapiens.
- Length: 718 amino acids.
- Top disease associations (Open Targets): body height, creatine kinase measurement and lip and oral cavity carcinoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Protein Smaug homolog 1 |
|---|---|
| UniProt accession | Q9UPU9 |
| Gene | SAMD4A |
| Organism | Homo sapiens |
| Length | 718 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (105)
Diseases linked to this target (Open Targets).
- body height · score 0.40
- creatine kinase measurement · score 0.36
- lip and oral cavity carcinoma · score 0.34
- aspartate aminotransferase measurement · score 0.33
- platelet crit · score 0.31
- BMI-adjusted waist circumference · score 0.29
- heel bone mineral density · score 0.29
- mean platelet volume · score 0.28
- vital capacity · score 0.20
- sitting height measurement · score 0.17
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9UPU9-F1 | alphafold | PREDICTED | 62.63 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9UPU9.
Amino-acid sequence (718 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SAMD4A?
The strongest Open Targets associations for SAMD4A are body height, creatine kinase measurement, lip and oral cavity carcinoma, aspartate aminotransferase measurement and platelet crit.
How long is the SAMD4A protein?
The Homo sapiens SAMD4A protein (UniProt Q9UPU9) is 718 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9UPU9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9UPU9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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