Trafficking kinesin-binding protein 1 (TRAK1)
Homo sapiens — UniProt Q9UPV9
Data last refreshed: (UniProt release unknown)
Key facts
Trafficking kinesin-binding protein 1 (TRAK1) is a protein from Homo sapiens identified by UniProt accession Q9UPV9, 953 residues long. MolForge cross-references it against 0 known binders and 155 disease associations.
- UniProt accession: Q9UPV9; gene symbol TRAK1.
- Organism: Homo sapiens.
- Length: 953 amino acids.
- Top disease associations (Open Targets): cancer, developmental and epileptic encephalopathy and electrocardiography.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Trafficking kinesin-binding protein 1 |
|---|---|
| UniProt accession | Q9UPV9 |
| Gene | TRAK1 |
| Organism | Homo sapiens |
| Length | 953 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (155)
Diseases linked to this target (Open Targets).
- cancer · score 0.54
- developmental and epileptic encephalopathy · score 0.49
- electrocardiography · score 0.42
- genetic disorder · score 0.41
- PR interval · score 0.40
- undetermined early-onset epileptic encephalopathy · score 0.37
- systolic blood pressure · score 0.28
- lung adenocarcinoma · score 0.23
- gut microbiome measurement · score 0.23
- whole body water mass · score 0.19
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9UPV9-F1 | alphafold | PREDICTED | 58.11 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9UPV9.
Amino-acid sequence (953 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with TRAK1?
The strongest Open Targets associations for TRAK1 are cancer, developmental and epileptic encephalopathy, electrocardiography, genetic disorder and PR interval.
How long is the TRAK1 protein?
The Homo sapiens TRAK1 protein (UniProt Q9UPV9) is 953 amino acids long.
Browse: Targets: T · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9UPV9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9UPV9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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