Coronin-2B (CORO2B)
Homo sapiens — UniProt Q9UQ03
Data last refreshed: (UniProt release unknown)
Key facts
Coronin-2B (CORO2B) is a protein from Homo sapiens identified by UniProt accession Q9UQ03, 480 residues long. MolForge cross-references it against 0 known binders and 88 disease associations.
- UniProt accession: Q9UQ03; gene symbol CORO2B.
- Organism: Homo sapiens.
- Length: 480 amino acids.
- Top disease associations (Open Targets): ringed hair disease, Griscelli syndrome type 3 and uncombable hair syndrome.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Coronin-2B |
|---|---|
| UniProt accession | Q9UQ03 |
| Gene | CORO2B |
| Organism | Homo sapiens |
| Length | 480 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (88)
Diseases linked to this target (Open Targets).
- ringed hair disease · score 0.08
- Griscelli syndrome type 3 · score 0.08
- uncombable hair syndrome · score 0.08
- familial idiopathic steroid-resistant nephrotic syndrome · score 0.07
- nephrotic syndrome · score 0.07
- Griscelli disease · score 0.07
- Griscelli disease type 3 · score 0.07
- protein measurement · score 0.07
- Microcephaly - albinism - digital anomalies · score 0.06
- microcephaly-albinism-digital anomalies syndrome · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9UQ03-F1 | alphafold | PREDICTED | 91.66 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9UQ03.
Amino-acid sequence (480 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CORO2B?
The strongest Open Targets associations for CORO2B are ringed hair disease, Griscelli syndrome type 3, uncombable hair syndrome, familial idiopathic steroid-resistant nephrotic syndrome and nephrotic syndrome.
How long is the CORO2B protein?
The Homo sapiens CORO2B protein (UniProt Q9UQ03) is 480 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9UQ03 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9UQ03 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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