MAPK/MAK/MRK overlapping kinase (MOK)
Homo sapiens — UniProt Q9UQ07
Data last refreshed: (UniProt release unknown)
Key facts
MAPK/MAK/MRK overlapping kinase (MOK) is a protein from Homo sapiens identified by UniProt accession Q9UQ07, 419 residues long. MolForge cross-references it against 0 known binders and 58 disease associations.
- UniProt accession: Q9UQ07; gene symbol MOK.
- Organism: Homo sapiens.
- Length: 419 amino acids.
- Target class: Kinase.
- Top disease associations (Open Targets): Red cell distribution width, urate measurement and body mass index.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | MAPK/MAK/MRK overlapping kinase |
|---|---|
| UniProt accession | Q9UQ07 |
| Gene | MOK |
| Organism | Homo sapiens |
| Length | 419 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | Kinase (inferred from UniProt keywords / EC) |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (58)
Diseases linked to this target (Open Targets).
- Red cell distribution width · score 0.45
- urate measurement · score 0.44
- body mass index · score 0.35
- mean corpuscular hemoglobin concentration · score 0.32
- neuroinflammatory disorder · score 0.32
- uric acid measurement · score 0.30
- mean corpuscular hemoglobin · score 0.29
- glomerular filtration rate · score 0.16
- mucopolysaccharidosis type 3 · score 0.12
- mean corpuscular volume · score 0.11
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9UQ07-F1 | alphafold | PREDICTED | 76.19 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9UQ07.
Amino-acid sequence (419 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with MOK?
The strongest Open Targets associations for MOK are Red cell distribution width, urate measurement, body mass index, mean corpuscular hemoglobin concentration and neuroinflammatory disorder.
How long is the MOK protein?
The Homo sapiens MOK protein (UniProt Q9UQ07) is 419 amino acids long.
Browse: Targets: M · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9UQ07 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9UQ07 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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