Dynamin-3 (DNM3)
Homo sapiens — UniProt Q9UQ16
Data last refreshed: (UniProt release unknown)
Key facts
Dynamin-3 (DNM3) is a protein from Homo sapiens identified by UniProt accession Q9UQ16, 869 residues long. MolForge cross-references it against 0 known binders and 136 disease associations.
- UniProt accession: Q9UQ16; gene symbol DNM3.
- Organism: Homo sapiens.
- Length: 869 amino acids.
- Top disease associations (Open Targets): mean platelet volume, platelet count and platelet component distribution width.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Dynamin-3 |
|---|---|
| UniProt accession | Q9UQ16 |
| Gene | DNM3 |
| Organism | Homo sapiens |
| Length | 869 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (136)
Diseases linked to this target (Open Targets).
- mean platelet volume · score 0.41
- platelet count · score 0.41
- platelet component distribution width · score 0.40
- neurodegenerative disease · score 0.39
- body height · score 0.32
- liver fibrosis measurement · score 0.31
- BMI-adjusted hip circumference · score 0.27
- pancreatic adenocarcinoma · score 0.27
- mitochondrial DNA measurement · score 0.25
- sitting height measurement · score 0.24
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9UQ16-F1 | alphafold | PREDICTED | 77.33 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9UQ16.
Amino-acid sequence (869 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with DNM3?
The strongest Open Targets associations for DNM3 are mean platelet volume, platelet count, platelet component distribution width, neurodegenerative disease and body height.
How long is the DNM3 protein?
The Homo sapiens DNM3 protein (UniProt Q9UQ16) is 869 amino acids long.
Browse: Targets: D · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9UQ16 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9UQ16 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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