Pregnancy-specific beta-1-glycoprotein 11 (PSG11)

About Pregnancy-specific beta-1-glycoprotein 11

Pregnancy-specific beta-1-glycoprotein 11 (PSG11) is a protein from Homo sapiens identified by UniProt accession Q9UQ72, 335 residues long. MolForge cross-references it against 0 known binders and 9 disease associations.

Target properties

Protein name	Pregnancy-specific beta-1-glycoprotein 11
UniProt accession	Q9UQ72
Gene	PSG11
Organism	Homo sapiens
Length	335 residues
Molecular weight	—
EC numbers	—
Target class	—
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (9)

Diseases linked to this target (Open Targets).

glioblastoma multiforme · score 0.18
breast adenocarcinoma · score 0.18
urate measurement · score 0.14
bone density · score 0.14
genetic disorder · score 0.12
head and neck squamous cell carcinoma · score 0.11
birth weight · score 0.03
visual perception measurement · score 0.02
blood protein measurement · score 0.02

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9UQ72-F1	alphafold	PREDICTED	88.03	—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9UQ72.

Amino-acid sequence (335 residues)

MGPLSAPPCT EHIKWKGLLL TALLLNFWNL PTTAQVMIEA QPPKVSEGKD VLLLVHNLPQ NLTGYIWYKG QIRDLYHYIT SYVVDGQIII YGPAYSGRET VYSNASLLIQ NVTREDAGSY TLHIIKRGDG TRGVTGYFTF TLYLETPKPS ISSSNLNPRE AMETVILTCN PETPDASYLW WMNGQSLPMT HRMQLSETNR TLFLFGVTKY TAGPYECEIW NSGSASRSDP VTLNLLHGPD LPRIFPSVTS YYSGENLDLS CFANSNPPAQ YSWTINGKFQ LSGQKLFIPQ ITPKHNGLYA CSARNSATGE ESSTSLTIRV IAPPGLGTFA FNNPT

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards