Cyclin-dependent kinase 11A (CDK11A)
Homo sapiens — UniProt Q9UQ88
Data last refreshed: (UniProt release unknown)
Key facts
Cyclin-dependent kinase 11A (CDK11A) is a protein from Homo sapiens identified by UniProt accession Q9UQ88, 783 residues long. MolForge cross-references it against 2 known binders and 24 disease associations.
- UniProt accession: Q9UQ88; gene symbol CDK11A.
- Organism: Homo sapiens.
- Length: 783 amino acids.
- Top disease associations (Open Targets): breast adenocarcinoma, total blood protein measurement and appendicular lean mass.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Cyclin-dependent kinase 11A |
|---|---|
| UniProt accession | Q9UQ88 |
| Gene | CDK11A |
| Organism | Homo sapiens |
| Length | 783 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (24)
Diseases linked to this target (Open Targets).
- breast adenocarcinoma · score 0.23
- total blood protein measurement · score 0.18
- appendicular lean mass · score 0.11
- systolic blood pressure · score 0.06
- palmoplantar keratoderma-XX sex reversal-predisposition to squamous cell carcinoma syndrome · score 0.03
- melanoma · score 0.03
- epidermodysplasia verruciformis · score 0.03
- alkaline phosphatase measurement · score 0.02
- type 2 diabetes mellitus · score 0.01
- chronic obstructive pulmonary disease · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9UQ88-F1 | alphafold | PREDICTED | 66.15 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9UQ88.
Amino-acid sequence (783 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CDK11A?
The strongest Open Targets associations for CDK11A are breast adenocarcinoma, total blood protein measurement, appendicular lean mass, systolic blood pressure and palmoplantar keratoderma-XX sex reversal-predisposition to squamous cell carcinoma syndrome.
How long is the CDK11A protein?
The Homo sapiens CDK11A protein (UniProt Q9UQ88) is 783 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9UQ88 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9UQ88 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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