Catenin delta-2 (CTNND2)
Homo sapiens — UniProt Q9UQB3
Data last refreshed: (UniProt release unknown)
Key facts
Catenin delta-2 (CTNND2) is a protein from Homo sapiens identified by UniProt accession Q9UQB3, 1225 residues long. MolForge cross-references it against 0 known binders and 240 disease associations.
- UniProt accession: Q9UQB3; gene symbol CTNND2.
- Organism: Homo sapiens.
- Length: 1225 amino acids.
- Top disease associations (Open Targets): Neurodevelopmental disorder, self reported educational attainment and genetic disorder.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Catenin delta-2 |
|---|---|
| UniProt accession | Q9UQB3 |
| Gene | CTNND2 |
| Organism | Homo sapiens |
| Length | 1225 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (240)
Diseases linked to this target (Open Targets).
- Neurodevelopmental disorder · score 0.41
- self reported educational attainment · score 0.38
- genetic disorder · score 0.38
- benign adult familial myoclonic epilepsy · score 0.37
- lung adenocarcinoma · score 0.33
- Abnormality of refraction · score 0.31
- macula measurement · score 0.29
- DNA methylation · score 0.29
- smoking status measurement · score 0.29
- adolescent idiopathic scoliosis · score 0.28
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9UQB3-F1 | alphafold | PREDICTED | 58.49 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9UQB3.
Amino-acid sequence (1225 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CTNND2?
The strongest Open Targets associations for CTNND2 are Neurodevelopmental disorder, self reported educational attainment, genetic disorder, benign adult familial myoclonic epilepsy and lung adenocarcinoma.
How long is the CTNND2 protein?
The Homo sapiens CTNND2 protein (UniProt Q9UQB3) is 1225 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9UQB3 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9UQB3 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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