BAR/IMD domain-containing adapter protein 2 (BAIAP2)
Homo sapiens — UniProt Q9UQB8
Data last refreshed: (UniProt release unknown)
Key facts
BAR/IMD domain-containing adapter protein 2 (BAIAP2) is a protein from Homo sapiens identified by UniProt accession Q9UQB8, 552 residues long. MolForge cross-references it against 0 known binders and 143 disease associations.
- UniProt accession: Q9UQB8; gene symbol BAIAP2.
- Organism: Homo sapiens.
- Length: 552 amino acids.
- Top disease associations (Open Targets): neuroticism measurement, body weight and body mass index.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | BAR/IMD domain-containing adapter protein 2 |
|---|---|
| UniProt accession | Q9UQB8 |
| Gene | BAIAP2 |
| Organism | Homo sapiens |
| Length | 552 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (143)
Diseases linked to this target (Open Targets).
- neuroticism measurement · score 0.44
- body weight · score 0.43
- body mass index · score 0.42
- lean body mass · score 0.41
- body height · score 0.40
- mathematical ability · score 0.37
- body fat percentage · score 0.37
- depressive symptom measurement · score 0.37
- wellbeing measurement · score 0.37
- attention deficit hyperactivity disorder · score 0.35
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9UQB8-F1 | alphafold | PREDICTED | 71.68 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9UQB8.
Amino-acid sequence (552 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with BAIAP2?
The strongest Open Targets associations for BAIAP2 are neuroticism measurement, body weight, body mass index, lean body mass and body height.
How long is the BAIAP2 protein?
The Homo sapiens BAIAP2 protein (UniProt Q9UQB8) is 552 amino acids long.
Browse: Targets: B · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9UQB8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9UQB8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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